(2R,4aR,8aS)-Decahydro-8a-hydroxy-4a-methyl-α,8-bis(methylene)-2-naphthaleneacetic acid - Names and Identifiers
Name | 5β-Hydroxycostic acid
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Synonyms | 5β-Hydroxycostic acid 5beta-Hydroxycostic acid (2R,4aR,8aS)-Decahydro-8a-hydroxy-4a-methyl-α,8-bis(methylene)-2-naphthaleneacetic acid 2-Naphthaleneacetic acid, decahydro-8a-hydroxy-4a-methyl-α,8-bis(methylene)-, (2R,4aR,8aS)- (2R,4aR,8aS)-Decahydro-8a-hydroxy-4a-methyl-alpha,8-bis(methylene)-2-naphthaleneacetic acid
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CAS | 132185-84-3
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(2R,4aR,8aS)-Decahydro-8a-hydroxy-4a-methyl-α,8-bis(methylene)-2-naphthaleneacetic acid - Physico-chemical Properties
Molecular Formula | C15H22O3
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Molar Mass | 250.33338 |
Density | 1.12±0.1 g/cm3(Predicted) |
Boling Point | 406.4±38.0 °C(Predicted) |
Appearance | Powder |
pKa | 4.42±0.11(Predicted) |
Storage Condition | 2-8℃ |
(2R,4aR,8aS)-Decahydro-8a-hydroxy-4a-methyl-α,8-bis(methylene)-2-naphthaleneacetic acid - Introduction
5β-Hydroxycostic acid (5β-Hydroxycostic acid) is an organic compound with the chemical formula C21H32O4. It is a derivative of Kosti acid, which forms a β-ring structure under acidic conditions and has a specific stereochemical configuration. The following are relevant Properties, Uses, methods and safety information:
Nature:
-Appearance: 5β-Hydroxycostic acid is a white solid.
-Solubility: Soluble in organic solvents such as chloroform, dichloromethane and ethanol at room temperature.
Use:
-Biological activity: 5β-Hydroxycostic acid is a natural product with antibacterial, anti-inflammatory and anti-tumor biological activities. It can be used as a raw material for drug research and drug development.
Method:
- 5β-Hydroxycostic acid can be obtained by a synthetic route starting from kestiic acid. First of all, Kosti acid undergoes a series of chemical reactions, such as hydrogenation, Ketonization, reduction, etc. Finally, the 5-position hydroxylation reaction was carried out under specific conditions to synthesize 5β-Hydroxycostic acid.
Safety Information:
- 5β-Hydroxycostic acid has no obvious harmfulness and toxicity under regular operating conditions.
-But as a chemical substance, pay attention to protective measures when using. Appropriate personal protective equipment such as lab gloves, glasses and lab coats should be worn.
-Avoid inhalation, ingestion or contact with skin during operation. If accidental contact occurs, immediately rinse the affected parts with plenty of water and seek medical treatment in time.
-The specific toxicity and safety information of the compound may depend on the specific use and concentration, so before use, it is recommended to refer to the relevant chemical safety data sheet for detailed information or to consult a professional for advice.
Last Update:2024-04-09 21:01:54